In multicellular animals, there has to be a balance between the free flow and clotting of blood. One molecule involved is von Willebrand factor, and the enzyme that cuts it down to size is now unveiled.
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Fosang, A., Smith, P. To clot or not. Nature 413, 475–476 (2001). https://doi.org/10.1038/35097196
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DOI: https://doi.org/10.1038/35097196
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