In times of starvation the liver turns into a glucose-producing organ, providing fuel for the brain. The hormonal signals that control this switch in glucose metabolism may converge on a single regulatory molecule.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Role of PCK1 gene on oil tea-induced glucose homeostasis and type 2 diabetes: an animal experiment and a case-control study
Nutrition & Metabolism Open Access 13 February 2019
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Tappy, L. & Minehira, K. Curr. Opin. Clin. Nutr. Metab. Care 4, 273–277 (2001).
Yoon, J. C. et al. Nature 413, 131–138 (2001).
Herzig, S. et al. Nature 413, 179–183 (2001).
Puigserver, P. et al. Cell 92, 829–839 (1998).
Wu, Z. et al. Cell 98, 115–124 (1999).
Michael, L. F. et al. Proc. Natl Acad. Sci. USA 98, 3820–3825 (2001).
Tcherepanova, I., Puigserver, P., Norris, J. D., Spiegelman, B. M. & McDonnell, D. P. J. Biol. Chem. 275, 16302–16308 (2000).
Puigserver, P. et al. Science 286, 1368–1371 (1999).
Monsalve, M. et al. Mol. Cell 6, 307–316 (2000).
Giacca, A., Fisher, S. J., McCall, R. H., Shi, Z. Q. & Vranic, M. Endocrinology 138, 999–1007 (1997).
Mitrakou, A. et al. New Engl. J. Med. 326, 22–29 (1992).
DeFronzo, R. A. Ann. Intern. Med. 131, 281–303 (1999).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Vidal-Puig, A., O'Rahilly, S. Controlling the glucose factory. Nature 413, 125–126 (2001). https://doi.org/10.1038/35093198
Issue Date:
DOI: https://doi.org/10.1038/35093198
