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A purgative mastery

Nature volume 412, pages 685–686 (2001)Cite this article

What is the molecular basis of the immunological self? The issue is rendered more complex by apparent exceptions to self-recognition. Healthy people can have antibodies in their serum that react with bodily components, and some autoreactive T cells are also present. Indeed, some have questioned the centrality of self–nonself discrimination and, as a passionate believer in its importance, I welcome the chance to revisit the subject in the molecular era.

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  1. Department of Pathology, University of Melbourne, Victoria, 3010, Australia

    G. J. V. Nossal

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  1. G. J. V. Nossal
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Nossal, G. A purgative mastery. Nature 412, 685–686 (2001). https://doi.org/10.1038/35089152

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