To a certain extent, the response of immune cells to infection is preset. T cells seem to be activated early on or not at all, and, once stimulated, embark on a complete programme of division and specialization.
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Welsh, R. Brief encounter. Nature 411, 541–542 (2001). https://doi.org/10.1038/35079229
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DOI: https://doi.org/10.1038/35079229