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Neurobiology

New memories from new neurons

Neurons are born throughout adulthood in specific regions of mammalian brains. It now turns out that — in rats at least — these new neurons are essential for the formation of one type of memory.

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Figure 1: New nerve cells that are born in the hippocampus of the adult mammalian brain are crucial in certain types of memory formation.

References

  1. Altman, J. & Das, G. D. J. Comp. Neurol. 124, 319–335 (1965).

    Article  CAS  PubMed  Google Scholar 

  2. Altman, J. J. Comp. Neurol. 137, 433–457 (1969).

    Article  CAS  PubMed  Google Scholar 

  3. Kaplan, M. S. & Hinds, J. W. Science 197, 1092–1094 (1977).

    Article  ADS  CAS  PubMed  Google Scholar 

  4. Luskin, M. B. Neuron 11, 173–189 (1993).

    Article  CAS  PubMed  Google Scholar 

  5. Lois, C. & Alvarez-Buylla, A. Proc. Natl Acad. Sci. USA 90, 2074–2077 (1993).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  6. Kuhn, H. G., Dickinson-Anson, H. & Gage, F. H. J. Neurosci. 16, 2027–2033 (1996).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Gould, E. et al. Proc. Natl Acad. Sci. USA 96, 5263–5267 (1999).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  8. Kornack, D. R. & Rakic, P. Proc. Natl Acad. Sci. USA 96, 5768–5773 (1999).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  9. Eriksson, P. S. et al. Nature Med. 4, 1313–1317 (1998).

    Article  CAS  PubMed  Google Scholar 

  10. Shors, T. J. et al. Nature 410, 372–376 (2001).

    Article  ADS  CAS  PubMed  Google Scholar 

  11. Gage, F. H. Science 287, 1433–1438 (2000).

    ADS  CAS  PubMed  Google Scholar 

  12. Goldman, S. A. & Nottebohm, F. Proc. Natl Acad. Sci. USA 80, 2390–2394 (1983).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  13. Barnea, A. & Nottebohm, F. Proc. Natl Acad. Sci. USA 91, 11217–11221 (1994).

    Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

  14. Scharff, C., Kirn, J. R., Grossman, M., Macklis, J. D. & Nottebohm, F. Neuron 25, 481–492 (2000).

    Article  CAS  PubMed  Google Scholar 

  15. Shin, J. J. et al. J. Neurosci. 20, 7404–7416 (2000).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Magavi, S. S., Leavitt, B. R. & Macklis, J. D. Nature 405, 951–955 (2000).

    Article  ADS  CAS  PubMed  Google Scholar 

Download references

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Correspondence to Jeffrey D. Macklis.

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Macklis, J. New memories from new neurons. Nature 410, 314–317 (2001). https://doi.org/10.1038/35066661

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