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The genome of an Escherichia coli strain that is emerging as a severe threat to human health has been sequenced. Comparing it with that of a harmless strain suggests why some forms of this bacterium cause disease.

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Figure 1: Model of the generation of genome islands specific to just one of a pair of related strains or species.


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Correspondence to Jonathan A. Eisen.

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Eisen, J. Gastrogenomics. Nature 409, 463–465 (2001).

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