New evidence suggests that RNA splicing, the removal of non-coding parts of a messenger RNA, is catalysed by an RNA component of the splicing machinery. This component binds a crucial metal ion.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Nilsen, T. W. in RNA Structure and Function (eds Simons, R. W. & Grunberg-Manago, M.) 279–307 (Cold Spring Harbor Laboratory Press, NY, 1998).
Staley, J. P. & Guthrie, C. Cell 92, 315–326 (1998).
Yean, S.-L, Wuenschell, G., Termini, J. & Lin, R.-J Nature 408, 881–884 ( 2000).
Sontheimer, E. J., Sun, S. & Piccirilli, J. A. Nature 388, 801– 805 (1997).
Feig, A. L. & Uhlenbeck, O. C. in The RNA World II (eds Gesteland, R. F., Cech, T. R. & Atkins, J. F.) 287– 319 (Cold Spring Harbor Laboratory Press, NY, 1999).
Collins, C. A. & Guthrie, C. Nature Struct. Biol. 7, 850–854 (2000).
Piccirilli, J. A., Vyle, J. S., Caruthers, M. H. & Cech, T. R. Nature 361, 85–88 ( 1994).
Shan, S.-O & Herschlag, D. RNA 6, 795–813 (2000).
Nissen, P., Hansen, J., Ban, N., Moore, P. B. & Steitz, T. A. Science 289, 920– 930 (2000).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Nilsen, T. The case for an RNA enzyme. Nature 408, 782–783 (2000). https://doi.org/10.1038/35048655
Issue Date:
DOI: https://doi.org/10.1038/35048655