The exquisite sensitivity of the polymerase chain reaction means DNA contamination can ruin an entire experiment. Tidiness and adherence to a strict set of protocols can avoid disaster.
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Kwok, S., Higuchi, R. Avoiding false positives with PCR. Nature 339, 237–238 (1989). https://doi.org/10.1038/339237a0
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DOI: https://doi.org/10.1038/339237a0