Abstract
Several glycoproteins that control blood-cell production and function have been purified and sequenced. The four colony-stimulating factors interact in a complex way to regulate the differentiation and maturation of the granulocyte and macrophage lineages and have potential applications for the clinical manipulation of blood-cell production.
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Metcalf, D. The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells. Nature 339, 27–30 (1989). https://doi.org/10.1038/339027a0
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DOI: https://doi.org/10.1038/339027a0
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