Abstract
Electron microscope tomography has been used to refine the structural analysis of individual RNP particles synthesized on Balbiani ring genes in Chironomus tentans. The spherical particles have a diameter of 500 Å and are composed of a thick RNP ribbon bent into an asymmetrical, four-domain, ring-like configuration. The first domain, containing the 5′ end of the transcript, and the fourth domain, containing the 3′ end, are close to each other.
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Skoglund, U., Andersson, K., Strandberg, B. et al. Three-dimensional structure of a specific pre-messenger RNP particle established by electron microscope tomography. Nature 319, 560–564 (1986). https://doi.org/10.1038/319560a0
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DOI: https://doi.org/10.1038/319560a0
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