Quaternary structure of the acetylcholine receptor

Abstract

The five membrane-spanning subunits of the acetylcholine receptor have been resolved in electron microscope images and are shown to lie at pentagonally symmetrical positions around the channel over a large fraction of their length. The channel consists of a wide synaptic portion and a narrow portion extending through the membrane into the interior of the cell.

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Brisson, A., Unwin, P. Quaternary structure of the acetylcholine receptor. Nature 315, 474–477 (1985). https://doi.org/10.1038/315474a0

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