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Genetic engineering and pharmaceuticals

Genetic engineering now allows biological synthesis and large-scale production of several proteins with therapeutic potential. The principal challenge in this sphere is to identify new, medically and commercially significant targets — the province of cell biologists, physiologists and biochemists. In the future, genetic engineering will surely provide invaluable tools for the study of the molecular basis of cellular control and pathophysiology, which will permit biochemists and medicinal chemists to design novel medicines.

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References

  1. Gruber, K. A., Whitaker, J. M. & Buckalew, V. M. Nature 287, 743–745, (1980).

    Article  ADS  CAS  Google Scholar 

  2. Scott, G. M. et al. Lancet ii, 186–188, 1982.

    Article  Google Scholar 

  3. Milstein, C. Scient. Am. 243(4), 66–74 (1980).

    Article  CAS  Google Scholar 

  4. Cuatrecasas, P. in Advances in Ezymology (ed. Meister, A.) 29–89 (Wiley, New York, 1972.

    Google Scholar 

  5. Bull. Wld Hlth Org. 61, 81–92 (1983).

  6. Arnon, R. A. Rev. Microbiol, 34, 593–618 (1980).

    Article  CAS  Google Scholar 

  7. Bittle, J. L. et al. Nature 298, 30 (1982).

    Article  ADS  CAS  Google Scholar 

  8. Audibert, F et al. Nature 289, 593 (1981).

    Article  ADS  CAS  Google Scholar 

  9. Ferreira, S. H. Br. J. Pharmac. 24, 163 (1965).

    CAS  Google Scholar 

  10. Cushman, D. W. et al. in Enzyme Inhibitors as Drugs (ed. Sandier, M.) 231–247 (Macmillan, London, (1980).

    Google Scholar 

  11. Beddell, C. R. et al. Proc. R. Soc. B198, 249–265 (1977).

    ADS  CAS  Google Scholar 

  12. Haggin, J. Chem. Engng News 9 May, 7–20 (1983).

  13. Elion, G. B. Am. J. Med. 73, 7–13 (1982).

    Article  CAS  Google Scholar 

Download references

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Vane, J., Cuatrecasas, P. Genetic engineering and pharmaceuticals. Nature 312, 303–305 (1984). https://doi.org/10.1038/312303a0

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