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Experimental chimaeras—removal of reproductive barrier between sheep and goat

Abstract

Following reciprocal embryo transfer between sheep and goats, the embryo of the foreign species is able to induce early pregnancy but the embryos do not survive beyond the first weeks of gestation1,2. Similar results have been obtained from hybridization experiments on sheep and goats. While the causes for early embryonic death of hybrid eggs from donor sheep are unknown, the reciprocal event has been associated with immunological implications2–7. As a means of overcoming the reproductive barrier between sheep and goats, we have transferred interspecific chimaeric embryos. We report here the birth of a goat kid from a sheep mother.

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References

  1. Warwick, B. L. & Berry, R. O. J. Hered. 40, 297–303 (1949).

    Article  CAS  Google Scholar 

  2. Hancock, J. L. & McGovern, P. T. Res. vet. Sci. 9, 411–415 (1968).

    Article  CAS  Google Scholar 

  3. Sokolovskaja, I. I. Anim. Breeding. Abstr. 10, 204 (1940).

    Google Scholar 

  4. Alexander, G., Williams, D. & Bailey, L. Aust. J. biol. Sci. 20, 1217–1220 (1967).

    Article  CAS  Google Scholar 

  5. Hancock, J. L., McGovern, P. T. & Stamp, J. T. J. Reprod. Fert. Suppl. 3, 29–36 (1968).

    Google Scholar 

  6. Dent, J., McGovern, P. T. & Hancock, J. L. Nature 231, 116–117 (1971).

    Article  ADS  CAS  Google Scholar 

  7. McGovern, P. T. J. Reprod. Fert. 34, 215–220 (1973).

    Article  CAS  Google Scholar 

  8. Meinecke-Tillmann, S. & Meinecke, B. Zentbl. VetMed. A30, 146–153 (1983).

    CAS  Google Scholar 

  9. Willadsen, S. M. & Fehilly, C. B. in Fertilization of the Human Egg in Vitro (eds Beier, H. M. & Lindner, H. R.) 353–357 (Springer, Berlin, (1983).

    Book  Google Scholar 

  10. Rossant, J., Maurer, V. M. & Croy, B. A. J. Embryol. exp. Morph. 69, 141–149 (1982).

    CAS  PubMed  Google Scholar 

  11. Amoroso, E. C. & Perry, J. S. in The Ovary Vol. 2, 2nd edn (eds Lord Zuckerman & Weir, B. J.) 315–398 (Academic, New York, (1977).

    Book  Google Scholar 

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Meinecke-Tillmann, S., Meinecke, B. Experimental chimaeras—removal of reproductive barrier between sheep and goat. Nature 307, 637–638 (1984). https://doi.org/10.1038/307637a0

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