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Regulation of nitrogen metabolism genes by nifA gene product in Klebsiella pneumoniae

Nature volume 301, pages 307313 (27 January 1983) | Download Citation

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Abstract

The Klebsiella pneumoniae nifA gene product, which is known to activate expression of the nitrogen fixation (nif) structural genes, is shown here also to be able to substitute for the product of the gene glnG (ntrC) in the regulation of other nitrogen metabolism genes. An evolutionary relationship between the nifA and glnG genes is suggested.

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References

  1. 1.

    & A. Rev. Microbiol. 35, 207–235 (1981).

  2. 2.

    et al. in Current Perspectives in Nitrogen Fixation (eds Gibson, A. H. & Newton, W. E.) 146–156 (Australian Academy of Science, Canberra, 1981).

  3. 3.

    & J. Bact. 144, 210–216 (1980).

  4. 4.

    et al. Nature 286, 128–132 (1980).

  5. 5.

    , , & Nature 294, 776–778 (1981).

  6. 6.

    , & Molec. gen. Genet. 184, 102–106 (1981).

  7. 7.

    , , , & Nature 290, 424–426 (1981).

  8. 8.

    et al. Molec. gen. Genet. 185, 75–81 (1982).

  9. 9.

    A. Rev. Biochem. 47, 1127–1162 (1978).

  10. 10.

    A. Rev. Genet. 16, 135–168 (1982).

  11. 11.

    & Proc. natn. Acad. Sci. U.S.A. 76, 4544–4548 (1979).

  12. 12.

    , , , & , Proc. natn. Acad. Sci. U.S.A. 76, 4576–4580 (1979).

  13. 13.

    & J. Bact. 142, 99 (1980).

  14. 14.

    & Molec. gen. Genet. 183, 289 (1981).

  15. 15.

    , & Molec. gen. Genet. 184, 213 (1981).

  16. 16.

    , , & J. Bact. 120, 815–821 (1982).

  17. 17.

    , , & Proc. natn. Acad. Sci. U.S.A. 74, 1662–1666 (1977).

  18. 18.

    & J. Bact. 133, 1429 (1978).

  19. 19.

    , , & Proc. natn. Acad. Sci. U.S.A. 78, 2135–2139 (1981).

  20. 20.

    , & J. Bact. 150, 202–213 (1982).

  21. 21.

    , & Proc. natn. Acad. Sci. U.S.A. 78, 3743–3747 (1981).

  22. 22.

    , & J. Bact. 150, 214–220 (1982).

  23. 23.

    , & Proc. natn. Acad. Sci. U.S.A. 77, 2636–2640 (1980).

  24. 24.

    , & J. Bact. 146, 740–745 (1981).

  25. 25.

    & Cell 12, 721–732 (1977).

  26. 26.

    , & J. Bact. 141, 213–222 (1980).

  27. 27.

    , & J. Bact. 143, 971–980 (1980).

  28. 28.

    et al. in Genetic Engineering (eds Setlow, J. K. & Hollaender, A.) 169–198 (Plenum, New York, 1982).

  29. 29.

    , , & (in the press).

  30. 30.

    , & J. Bact. 144, 348–357 (1981).

  31. 31.

    & J. Bact. 144, 744–751 (1980).

  32. 32.

    , , & J. Bact. 134, 569–577 (1978).

  33. 33.

    , & J. Bact. (in the press).

  34. 34.

    & Meth. Enzym. 68, 473–482 (1979).

  35. 35.

    & J. Bact. 151, 1299–1313 (1982).

  36. 36.

    & in Cold Spring Harb. Symp. quant. Biol. 45, 487–499 (1981).

  37. 37.

    & in Biology of Inorganic Nitrogen and Sulfur (eds Bothe, H. & Trebst, A.) 276–286 (Springer, Berlin, 1981).

  38. 38.

    & in Glutamine: Metabolism, Enzymology, and Regulation (eds Mora, J. & Palacios, R.) 61 (Academic, New York, 1980).

  39. 39.

    & A. Rev. Microbiol. 32, 519–560 (1978).

  40. 40.

    & Microbiol. Rev. 44, 1–56 (1980).

  41. 41.

    & Jap. J. Microbiol. 14, 129–141 (1970).

  42. 42.

    , & Proc. natn. Acad. Sci. U.S.A. (submitted).

  43. 43.

    et al. Proc. natn. Acad. Sci. U.S.A. (submitted).

  44. 44.

    & Biochem. biophys. Acta 437, 313–321 (1976).

  45. 45.

    , , & Nature 301, 302–307 (1983).

  46. 46.

    EMBO J. (in the press).

  47. 47.

    & Molec. gen. Genet. 180, 165–175 (1980).

  48. 48.

    , , , & J. Bact. 120, 815–821 (1974).

  49. 49.

    in Experiments in Molecular Genetics, 162–172 (Cold Spring Harbor Laboratory, New York, 1972).

  50. 50.

    , , , & J. Bact. 129, 1001–1009 (1977).

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    • David W. Ow
    •  & Frederick M. Ausubel

    Present address: Department of Molecular Biology, Massachusetts General Hospital, Jackson 11, Boston, Massachusetts 02114, USA.

Affiliations

  1. Department of Biology, Harvard University, Cambridge, Massachusetts 02138, USA

    • David W. Ow
    •  & Frederick M. Ausubel

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https://doi.org/10.1038/301307a0

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