Article | Published:

Rearranged mitochondrial genes in the yeast nuclear genome

Nature volume 301, pages 296301 (27 January 1983) | Download Citation

Subjects

Abstract

We have found a contiguous DNA sequence in the yeast nuclear genome with extensive homology to non-contiguous yeast mitochondrial DNA sequences. Closely linked to this nuclear sequence in some, but not all, yeast strains is a tandem pair of transposable (Ty) elements. Certain features of the content and organization of this nuclear DNA sequence suggest that it may have originated from petite mitochondrial DNA which integrated into the nuclear genome.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    & Cell 15, 705–723 (1978).

  2. 2.

    & Trends biochem. Sci. 4, 110–113 (1979).

  3. 3.

    , & A. Rev. Biochem. 48, 419–441 (1979).

  4. 4.

    , & J. biol. Chem. 254, 12653–12661 (1979).

  5. 5.

    & J. biol. Chem. 254, 12662–12669 (1979).

  6. 6.

    , & Molec. gen. Genet. 174, 339–342 (1979).

  7. 7.

    , & J. molec. Biol. 107, 223–253 (1876).

  8. 8.

    & J. biol. Chem. 356, 7064–7067 (1981).

  9. 9.

    , , & in Genetics and Biogenesis of Chloroplasts and Mitochondria (eds Bucher, T., Neupert, W., Sebald, W. & Werner, S.) 569–572 (North-Holland, Amsterdam, 1976).

  10. 10.

    , , & in The Organization and Expression of the Mitochondrial Genome (eds Kroon, A. M. & Saccone, I. C.) 675–694 (Elsevier, Amsterdam, 1980).

  11. 11.

    , , & in Mitochondrial Genes (eds Slonimski, P. P., Borst, P. & Attardi, G.) 457–470 (Cold Spring Harbor Laboratory, New York, 1982).

  12. 12.

    , , , & Cell 30, 617–626 (1982).

  13. 13.

    et al. Nature 290, 457–465 (1981).

  14. 14.

    et al. J. molec. Biol. 156, 683–717 (1982).

  15. 15.

    , , , & Cell 26, 167–180 (1981).

  16. 16.

    & Biochemistry 21, 3188–3195 (1982).

  17. 17.

    , & Cell 22, 333–348 (1980).

  18. 18.

    et al. in Mitochondrial Genes (eds Slonimski, P. P., Borst, P. & Attardi, G.) 185–199 (Cold Spring Harbor Laboratory, New York, 1982).

  19. 19.

    , , & Cell 29, 527–536 (1982).

  20. 20.

    , & Nature 282, 189–194 (1979).

  21. 21.

    et al. Proc. natn. Acad. Sci. U.S.A. 77, 3167–3170 (1980).

  22. 22.

    & Gene 12, 257–265 (1980).

  23. 23.

    , , , & Proc. natn. Acad. Sci. U.S.A. 77, 3159–3163 (1980).

  24. 24.

    , & Biochim. biophys. Acta 652, 234–239 (1981).

  25. 25.

    & Eur. J. Biochem. 54, 97–106 (1975).

  26. 26.

    , & Nature 298, 187–189 (1982).

  27. 27.

    & Proc. natn. Acad. Sci. U.S.A. 77, 3942–3946 (1980).

  28. 28.

    et al. Nature 292, 75–78 (1981).

  29. 29.

    , & Cell 16, 739–751 (1979).

  30. 30.

    , , & Science 209, 1375–1379 (1980).

  31. 31.

    & J. molec. Biol. 156, 293–307 (1982).

  32. 32.

    , , & J. molec. Biol. 115, 675–694 (1977).

  33. 33.

    , , & Curr. Genet. 2, 27–38 (1980).

  34. 34.

    , & J. biol. Chem. 256, 6496–6501 (1981).

  35. 35.

    J. molec. Evol. 9, 25–35 (1976).

  36. 36.

    & J. biol. Chem. 255, 9828–9837 (1980).

  37. 37.

    et al. in The Organization and Expression of the Mitochondrial Genome (eds Kroon, A. M. & Saccone, I. C.) 21–31 (Elsevier, Amsterdam, 1980).

  38. 38.

    & Plasmid 2, 155–181 (1979).

  39. 39.

    , & Nature 283, 218–220 (1980).

  40. 40.

    & in Mitochondrial Genes (eds Slominski, P. P., Borst, P., & Attardi, G.) 279–284 (Cold Spring Harbor Laboratory, New York, 1982).

  41. 41.

    , , & Nature 286, 222–226 (1980).

  42. 42.

    , & Proc. natn. Acad. Sci. U.S.A. 77, 2806–2809 (1980).

  43. 43.

    , , , & Nature 296, 321–325 (1982).

  44. 44.

    , & Science 217, 549–552 (1982).

  45. 45.

    , & Cell 26, 141–142 (1981).

  46. 46.

    , , & Cell 22, 777–785 (1980).

  47. 47.

    et al. Cell 26, 11–18 (1981).

  48. 48.

    Frederick, J.F. (ed.) Origins and Evolution of Eukaryotic Intracellular Organelles (Annals of the New York Academy of Sciences, 1981).

  49. 49.

    et al. Cell 20, 555–566 (1980).

  50. 50.

    , , , & J. cell. Biochem. Suppl. 6, 817 (1982).

  51. 51.

    , , & Biochim. biophys. Acta 610, 221–228 (1980).

  52. 52.

    & Proc. natn. Acad. Sci. U.S.A. 77, 6541–6545 (1980).

  53. 53.

    & Meth. Enzym. 65, 499–560 (1980).

Download references

Author information

Affiliations

  1. Division of Molecular Biology, Department of Biochemistry, The University of Texas Health Science Center at Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75235, USA

    • Frances Farrelly
    •  & Ronald A. Butow

Authors

  1. Search for Frances Farrelly in:

  2. Search for Ronald A. Butow in:

About this article

Publication history

Received

Accepted

Published

DOI

https://doi.org/10.1038/301296a0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.