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Interacting genes in nematode dauer larva formation


The dauer larva of Caenorhabditis elegans is a developmentally arrested stage induced by starvation or overcrowding. Mutant genes controlling the ability to form dauer larvae interact in a way which allows them to be ordered in a pathway. Mutant phenotypes suggest that the pathway corresponds to neural processing of environmental stimuli.

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Riddle, D., Swanson, M. & Albert, P. Interacting genes in nematode dauer larva formation. Nature 290, 668–671 (1981).

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