Abstract
Four mutations of the a mating type locus of Saccharomyces cerevisiae have been analysed to determine their relationship to the a mating type locus. Matα+ recombinants are produced by matα2−/MATa but not by matα1−/MATa diploids. MATα and MATa thus contain regions of homology (coding for at least part of MATα2) and regions of non-homology (coding for at least part of MATα1)—the genetic determinant for cell type is larger than the non-homologous sequence seen by DNA–DNA heteroduplexes and genetic analysis. The segment transposed in mating type interconversion includes both types of sequence.
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Sprague, G., Rine, J. & Herskowitz, I. Homology and non-homology at the yeast mating type locus. Nature 289, 250–252 (1981). https://doi.org/10.1038/289250a0
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DOI: https://doi.org/10.1038/289250a0
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