Letter | Published:

Do ‘lipidic particles’ represent intermembrane attachment sites?

Abstract

Although freeze-fracture electron microscopy is normally analysed with the presumption that particles represent proteins embedded within the membrane, particles which appeared to represent inverted lipid micelles within membranes have been reported1–4. I have now confirmed the occurrence of particles in protein-free liposomes, but have found that they behave like intermembrane attachment sites rather than structures within a membrane.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Verkleij, A. J., Mombers, C., Leunissen-Bijvelt, J. & Ververgaert, P. J. J. Th. Nature 279, 162–163 (1979).

  2. 2

    DeKruijff, B. et al. Biochim. biophys. Acta 555, 200–209 (1979).

  3. 3

    Verkleij, A. J., Mombers, C., Gerritsen, W. J., Leunissen-Bijvelt, L. & Cullis, P. R. Biochim. biophys. Acta 555, 358–361 (1979).

  4. 4

    De Kruijff, B., Cullis, P. R. & Verkleij, A. J. Trends biol. Sci. 5, 79–81 (1980).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.