Abstract
Vaccinia virus DNA contains a long inverted terminal repetition of MW ∼6.8 × 106. A fragment of MW 6.3 × 106 from this repetition has been cloned in coliphage λ and used to isolate RNA from virus-infected cells. Electron microscopy indicates that early RNAs are transcribed from the repeated sequence and cell-free translation shows that the RNAs code for polypeptides.
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Wittek, R., Barbosa, E., Cooper, J. et al. Inverted terminal repetition in vaccinia virus DNA encodes early mRNAs. Nature 285, 21–25 (1980). https://doi.org/10.1038/285021a0
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DOI: https://doi.org/10.1038/285021a0
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