Abstract
Single-stranded DNA, whether homologous or not, stimulates purified Escherichia coli recA protein to unwind duplex DNA. This helps to explain how recA promotes a search for homology in genetic recombination. As oligodeoxynucleotides also stimulate unwinding, a common mechanism may relate the function of recA protein in recombination to other functions (SOS) induced by oligonucleotides.
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Cunningham, R., Shibata, T., DasGupta, C. et al. Single strands induce recA protein to unwind duplex DNA for homologous pairing. Nature 281, 191–195 (1979). https://doi.org/10.1038/281191a0
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DOI: https://doi.org/10.1038/281191a0
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