Abstract
Regulation of plasma membrane receptors for peptide hormones by the prevailing ligand concentration often causes altered target cell function. Receptor number is determined by hormone-induced changes in membrane conformation, irreversible ligand binding, and processing of ligand–receptor complexes during hormone action.
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Catt, K., Harwood, J., Aguilera, G. et al. Hormonal regulation of peptide receptors and target cell responses. Nature 280, 109–116 (1979). https://doi.org/10.1038/280109a0
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DOI: https://doi.org/10.1038/280109a0
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