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t-Haplotypes of the mouse may involve a change in intercalary DNA

Nature volume 279, pages 38–42 (1979)Cite this article

Abstract

The naturally occurring t-haplotypes of the mouse exhibit a set of peculiar genetic properties, including strong suppression of crossing over in the segment of chromosome 17 between the loci of T and H–2. Study of the genetics of mutant haplotypes suggests that the observed effects on meiosis and embryonic development may be due to an altered form of intercalary DNA (iDNA) in the relevant chromosomal region (band 17B).

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Author information

Authors and Affiliations

  1. MRC Radiobiology Unit, Harwell, Didcot, Oxon, UK

    Mary F. Lyon, E. P. Evans, Susan E. Jarvis & Irene Sayers

  2. Sir William Dunn School of Pathology, South Parks Road, Oxford, UK

    E. P. Evans

Authors
  1. Mary F. Lyon
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  2. E. P. Evans
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  3. Susan E. Jarvis
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  4. Irene Sayers
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Lyon, M., Evans, E., Jarvis, S. et al. t-Haplotypes of the mouse may involve a change in intercalary DNA. Nature 279, 38–42 (1979). https://doi.org/10.1038/279038a0

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