Abstract
Specific antibodies have been used to show that in adult skeletal muscle the slow and fast forms of the components of the troponin complex are located in type I and type II fibres respectively, α-Tropomyosin is restricted to type II cells. During development, as a result of changes in innervation and in certain diseased stages, both the slow and fast polymorphic forms of the troponin components are present in the same cell.
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References
Padykula, H. A. & Herman, E. J. Histochem. Cytochem. 3, 170–183 (1955).
Pette, D. & Schnez, V. Histochemistry 54, 97–107 (1977).
Rubinstein, N. et al. J. Cell. Biol. 79, 252–261 (1978).
Gauthier, G. F. & Lowey, S. J. Cell. Biol. 74, 760–779 (1977).
Pette, D. & Schnez, V. FEBS Lett. 83, 128–130 (1977).
Weeds, A. G., Hall, R. & Spurway, N. C. S. FEBS Lett. 49, 320–324 (1975).
Weeds, A. G. & Taylor, R. S. Nature 257, 54–56 (1975).
Wagner, P. FEBS Lett. 81, 81–85 (1977).
Barany, M. J. gen. Physiol. 50, suppl. part 2, 197–218 (1967).
Syska, H., Perry, S. V. & Trayer, I. P. FEBS Lett. 40, 253–257 (1974).
Wilkinson, J. M. & Grand, R. J. A. Nature 271, 31–35 (1978).
Hitchcock, S. E. Biochemistry 12, 2509–2515 (1973).
Perry, S. V. & Cole, H. A. Biochem. J. 141, 733–743 (1974).
Cole, H. A. & Perry, S. V. Biochem. J. 149, 525–533 (1975).
Brekke, C. J. & Greaser, M. L. J. biol. Chem. 251, 866–871 (1976).
Clarke, F. M., Lovell, S. J., Masters, C. J. & Winzor, D. J. Biochim. biophys. Acta 427, 617–626 (1976).
Wilkinson, J. M. Biochem. J. 169, 229–238 (1978).
Collins, J. H., Potter, J. D., Horn, M. J., Wilshire, G. & Jackman, N. FEBS Lett. 36, 268–272 (1973).
van Eerd, J. P. & Takahashi, K. Biochem. biophys. Res. Commun. 64, 122–127 (1975).
Head, J. F., Weeks, R. A. & Perry, S. V. Biochem. J. 161, 371–382 (1977).
Cummins, P. & Perry, S. V. Biochem. J. 133, 765–777 (1973).
Cummins, P. & Perry, S. V. Biochem. J. 141, 43–49 (1974).
Romero-Herrera, A. E., Castillo, O. & Lehmann, H. J. mol. Biol. 8, 251–270 (1976).
Cummins, P. & Perry, S. V. Biochem. J. 171, 251–259 (1978).
Perry, S. V. in Exploratory Concepts in Muscular Dystrophy II, (ed. Milhorat, A. T.) 319–328 (Excerpta Medica, Amsterdam, 1974).
Masaki, T. & Yoshikazi, C. J. Biochem. 76, 123–131 (1974).
Gauthier, G. F., Lowey, S. & Hobbs, A. W. Nature 274, 25–29 (1978).
Pelloni-Mueller, G., Ermini, M. & Jenny, E. FEBS Lett. 67, 68–74 (1976).
Rubinstein, N. A., Pepe, F. A. & Holtzer, H. Proc. natn. Acad. Sci. U.S.A. 74, 4524–4527 (1977).
Trayer, I. P. & Perry, S. V. Biochem. Zt. 345, 87–100 (1966).
Sreter, F. A., Balint, M. & Gregely, J. J. Devl. Biol. 46, 317–325 (1975).
Dhoot, G. K., Gell, P. G. H. & Perry, S. V. Expl. Cell. Res. 117, 357–370 (1978).
Margossian, S. S. & Cohen, C. J. molec. Biol. 81, 409–413 (1973).
Hirabayashi, T. & Perry, S. V. Biochim. biophys. Acta 351, 273–289 (1974).
Wilkinson, J. M. FEBS Lett. 70, 254–256 (1976).
Catty, D., Kennedy, J. F., Drew, R. L. & Chotun, H. J. immun. Meth. 2, 353–369 (1973).
Nakane, P. K. & Kawaoi, A. J. J. Histochem. Cytochem. 22, 1084–1091 (1974).
Graham, R. C. Jr. & Karnovsky, M. J. J. Histochem. Cytochem. 14, 291 (1966).
Dubowitz, V. & Brooke, M. H. Muscle Biopsy: A Modern Approach (S. B. Saunders,London, 1973).
Whalen, R. G., Butler-Browne, B. S. & Gros, F. Proc. natn. Acad. Sci. U.S.A. 73, 2018–2022 (1976).
Elzinga, M. & Lu, R. C. in Contractile Systems in Non-Muscle Tissues (eds Perry, S. V.,Margreth A. & Adelstein, R. S.) 29–37 (North-Holland, Amsterdam, 1976).
Amphlett, G. W., Syska, H. & Perry, S. V. FEBS Lett. 63, 22–26 (1976).
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Dhoot, G., Perry, S. Distribution of polymorphic forms of troponin components and tropomyosin in skeletal muscle. Nature 278, 714–718 (1979). https://doi.org/10.1038/278714a0
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DOI: https://doi.org/10.1038/278714a0
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