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Nucleotide sequence of a region of human mitochondrial DNA containing the precisely identified origin of replication

Naturevolume 277pages192198 (1979) | Download Citation

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Abstract

A fragment of HeLa cell mitochondrial DNA containing the origin of replication has been sequenced. The precise position of the origin in this sequence has been identified by determining the nucleotide order in the 5′-end proximal portion of the heavy strand initiation fragment (7S DNA), and by aligning the two sequences.

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  1. Division of Biology, California Institute of Technology, Pasadena, California, 91125

    • Stephen Crews
    • , Deanna Ojala
    • , James Posakony
    • , Jerry Nishiguchi
    •  & Giuseppe Attardi

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https://doi.org/10.1038/277192a0

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