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Surface antibodies of human myelogenous leukaemia leukocytes reactive with specific type-C viral reverse transcriptases

Nature volume 276, pages 230–236 (1978)Cite this article

Abstract

Purified immunoglobin G (IgG)from patients with chronic myelogenous leukaemia specifically neutralised RT from feline leukaemia virus while purified IgG from other types of leukaemias and from normal blood cells were less reactive and in some cases preferentially reacted with RT from horizontally transmitted primate type-C viruses (simian sarcoma virus–gibbon ape leukaemia virus group). This indicates the presence of a heterogeneous immune response to RT or to an RT-like molecule in humans.

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Authors and Affiliations

  1. National Cancer Institute, National Institutes of Health, Laboratory of Tumor Cell Biology, Bethesda, Maryland, 20014

    Paul C. Jacquemin, Carl Saxinger & Robert C. Gallo

Authors
  1. Paul C. Jacquemin
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  2. Carl Saxinger
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  3. Robert C. Gallo
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Jacquemin, P., Saxinger, C. & Gallo, R. Surface antibodies of human myelogenous leukaemia leukocytes reactive with specific type-C viral reverse transcriptases. Nature 276, 230–236 (1978). https://doi.org/10.1038/276230a0

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