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Sequence of the lacI gene

Nature volume 274, pages 765769 (24 August 1978) | Download Citation

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Abstract

The structural gene for the lac repressor of Escherichia coli, the lacI gene has been sequenced. This 1,080 base pair region of the E. coli chromosome codes for the lac repressor protein of 360 amino acids. The DNA sequence largely confirms but extends the previously reported protein sequence and allows a structural analysis of genetic phenomena.

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Author notes

    • Philip J. Farabaugh

    Present address: Section on Botany, Genetics, and Development, Cornell University, Ithaca, New York 14850.

Affiliations

  1. Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, Massachusetts 02138

    • Philip J. Farabaugh

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DOI

https://doi.org/10.1038/274765a0

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