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An association between actin and the major histocompatibility antigen H–2

Abstract

P815 cells spontaneously shed material (exfoliate) in which actin is the major protein. The exfoliate also contains H–2. The association between actin and H–2 is stable even in the presence of detergent, indicating that protein–protein interactions exist between the actin and H–2. The exfoliate probably consists of highly purified microvilli.

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