Abstract
Sedimentation analysis of mRNA from RSV-infected chick cells suggests that Pr76, the precursor to the virus structural proteins, is synthesised on a mRNA of similar size to virion RNA, whereas a protein with molecular weight 70,000 tentatively identified as the non-glycosylated precursor to the viral glycoprotein, gp85, is synthesised on a smaller size class of mRNA.
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References
Joho, R. H., Billeter, M. A. & Weissmann, C. Proc. natn. Acad. Sci. U.S.A. 72, 4772–4776 (1975).
King, A. M. Q. J. biol. Chem. 251, 141–149 (1976).
Mangel, W. F., Delius, H. & Duesberg, P. Proc. natn. Acad. Sci. U.S.A. 71, 4541–4545 (1974).
Wang, L.-H., Duesberg, P., Beemon, K. & Vogt, P. K. J. Virol. 16, 1051–1070 (1975).
Wang, L.-H., Duesberg, P. H., Kawai, S. & Hasafusa, H. Proc. natn. Acad. Sci. U.S.A. 73, 447–451 (1976).
Pawson, T., Martin, G. S. & Smith, A. E. J. Virol. 19, 950–967 (1976).
von der Helm, K. & Duesberg, P. H. Proc. natn. Acad. Sci., U.S.A. 72, 614–618 (1975).
Vogt, V. M., Eisenmann, R. & Diggelmann, H. J. molec. Biol. 96, 471–493 (1976).
Verma, I. M., Mason, W. S., Drost, S. D. & Baltimore, D. Nature 251, 27–31 (1974).
Coffin, J. & Temin, H. M. J. Virol. 9, 766–775 (1972).
Fan, H. & Baltimore, D. J. molec. Biol. 80, 93–117 (1973).
Fan, H. & Mueller-Lantzsch, N. J. Virol. 18, 401–410 (1976).
Gielkins, A. L. J., Salden, M. & Bloemendal, H. Proc. natn. Acad. Sci. U.S.A. 71, 1093–1097 (1974).
Shanmugam, G., Bhadrin, S. & Green, M. Biochem. biophys. Res. Commun. 56, 697–702 (1974).
Tsuchida, N. & Green, M. Virology 59, 258–265 (1974).
Smith, A. E., Kamen, R., Mangel, W. F., Shure, H. & Wheeler, T. Cell 9, 481–487 (1976).
MacNaughton, K. B., Freeman, K. B. & Bishop, J. O. Cell 1, 117–125 (1974).
Laskey, R. A. & Mills, A. D. Eur. J. Biochem. 56, 335–341 (1975).
Rohrschneider, L., Bauer, H. & Bolognesi, D. P. Virology 67, 234–241 (1975).
Anderson, C. W., Lewis, J. B., Atkins, J. F. & Gesteland, R. F. Proc. natn. Acad. Sci. U.S.A. 71, 2756–2760 (1974).
Schreier, M. H. & Staehelin, T. J. molec. Biol. 73, 329–349 (1973).
Kessler, S. W. J. Immun. 115, 1617–1624 (1975).
Besmer, P., et al. Cold Spring Harb. Symp. quant. Biol. 39, 1103–1107 (1974).
Coffin, J. M., Parsons, J. T., Rymo, L., Haroz, R. K. & Weissmann, C. J. molec. Biol. 86, 373–396 (1974).
Green, M., Rokutanda, H. & Rokutanda, M. Nature new Biol. 230, 229–232 (1971).
Leong, J.-A., et al. J. Virol. 9, 891–902 (1972).
Parsons, J. T., Coffin, J. M., Haroz, R. K., Bromley, P. A. & Weissmann, C. J. Virol. 11, 761–774 (1973).
Halpern, S. M., Bolognesi, D. P. & Lewandowski, L. J. Proc. natn. Acad. Sci. U.S.A. 71, 2342–2346 (1974).
Glanville, N., Ranki, M., Morser, J., Kääriäinen, L. & Smith, A. E. Proc. natn. Acad. Sci. U.S.A., 73, 3059–3063 (1976).
Arlinghaus, R. B., Naso, R. B., Jamjoom, G. A., Arcement, L. J. & Karshin, W. L. in ICN-UCLA Symposia on Molecular and Cellular Biology (eds Baltimore, D. & Huang, A.) (Academic, New York, in the press).
Kerr, I. A., Olshevsky, U., Lodish, H. F. & Baltimore, D. J. Virol. 18, 627–635 (1976).
Weiner, A. M. & Weber, K. Nature new Biol. 234, 206–209 (1971).
Paucha, E., Seehafer, J. & Colter, J. S. Virology 61, 315–326 (1974).
Gielkins, A. L. J., van Zanne, D., Bloemers, H. P. & Bloemendal, H. Proc. natn. Acad. Sci. U.S.A. 73, 356–360 (1976).
Salden, M. H. L., Selten-Versteegen, A.-M. & Bloemendal, H. Biochem. biophys. Res. Commun. 72, 610–618 (1976).
Mueller-Lantzsch, N. & Fan, H. Cell 9, 579–588 (1976).
Stacey, D. W., Allfrey, V. G. & Manafusa, M. Proc. natn. Acad. Sci. U.S.A. 74, 1614–1618 (1977).
Van Zaane, D., Gielkens, A. L. J., Hesselink, W. G. & Bloemers, H. P. J. Proc. natn. Acad. Sci. U.S.A. 74, 1855–1859 (1977).
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Pawson, T., Harvey, R. & Smith, A. The size of Rous sarcoma virus mRNAs active in cell-free translation. Nature 268, 416–420 (1977). https://doi.org/10.1038/268416a0
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DOI: https://doi.org/10.1038/268416a0
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