Abstract
Mathematical models of homologous but unequal crossing-over between sister chromatids are presented. For mispairing by one repeat, the evolution of a multigene family by unequal crossing over can be represented by a linear birth–death process. The fixation rate of one repeat in a multigene family is estimated. For mispairing by more than one repeat, some approximate results are obtained.
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Perelson, A., Bell, G. Mathematical models for the evolution of multigene families by unequal crossing over. Nature 265, 304–310 (1977). https://doi.org/10.1038/265304a0
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DOI: https://doi.org/10.1038/265304a0
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