Abstract
It is shown that electrophoretic genetic distance estimates are highly correlated with albumin immunological distances between the same pairs of species. The bimodality of rates of electrophoretic differentiation at various loci is then documented and the electrophoretic clocks involved are calibrated. The differences between the systematics and population genetics uses of electrophoretic data are then discussed. Finally, a direct electrophoretic test of the neutral alleles hypothesis is presented and exemplified on a set of Thomomys bottae-umbrinus data.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Nei, M., Am. Nat., 105, 385–398 (1971).
Nei, M., Am. Nat., 106, 283–292 (1972).
Sarich, V. M., Syst. Zool., 18, 286–295 (1969).
Champion, A. B., Soderberg, K. L., Wilson, A. C., and Ambler, R. P., J. molec. Evol., 5, 291–305 (1975).
Johnson, W. E., and Selander, R. K., Syst. Zool., 20, 377–405 (1971).
Johnson, W. E., Selander, R. K., Smith, M. H., and Kim, Y. J., Univ. Texas Publ., 7213, 297–305 (1972).
Smith, M. H., Selander, R. K., and Johnson, W. E., J. Mamm., 54, 1–13 (1973).
Case, S. M., Haneline, P. G., and Smith, M. F., Syst. Zool., 24, 281–295 (1975).
Yang, S. Y., Soule, M., and Gorman, G. C., Syst. Zool., 23, 387–399 (1974).
Dickerson, R. E., J. molec. Evol., 1, 26–45 (1971).
Langley, C. H., and Fitch, W. M., J. molec. Evol., 3, 161–178 (1974).
Maxson, L. R., Sarich, V. M., and Wilson, A. C., Nature, 255, 397–400 (1975).
Ruth, R. C., and Wold, F., Comp. Biochem. Physiol., 54 B, 1–6 (1976).
King, M.-C., thesis, Univ. California, Berkeley (1974).
King, M.-C., and Wilson, A. C., Science, 188, 107–118 (1975).
Sarich, V. M., Nature, 245, 218–220 (1973).
Cronin, J. E., and Sarich, V. M., J. Hum. Evol., 4, 357–375 (1975).
Gillespie, J. H., and Kojima, K., Proc. natn. Acad. Sci. U.S.A., 61, 582–585 (1968).
Kojima, K., Gillespie, J. H., and Tobari, Y. N., Biochem. Genet., 4, 627–63 (1970).
Johnson, G. B., Science, 184, 28–37 (1974).
Smith, J. K., and Zimmerman, E. G., Comp. Biochem. Physiol., 53 B, 319–324 (1976).
Nevo, E., Kim, Y. J., Shaw, C. R., and Thaeler, C. S., Jr, Evol., 28, 1–23 (1974).
Zimmerman, E. G., Hart, B. J., and Kilpatrick, C. W., Comp. Biochem. Physiol., 52 B, 541–545 (1975).
Patton, J. L., MacArthur, H., and Yang, S. Y., J. Mammal., 57, 159–163 (1976).
Cronin, J. E., and Sarich, V. M., Nature, 260, 700–702 (1976).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sarich, V. Rates, sample sizes, and the neutrality hypothesis for electrophoresis in evolutionary studies. Nature 265, 24–28 (1977). https://doi.org/10.1038/265024a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/265024a0
This article is cited by
-
Intercontinental genetic divergence of Castanea species in eastern Asia and eastern North America
Heredity (2003)
-
Genetic variation and natural hybridization betweenOrchis laxiflora andOrchis palustris (Orchidaceae)
Plant Systematics and Evolution (1996)
-
Population differentiation and taxonomic status of the exploited limpet Patella candei in the Macaronesian islands (Azores, Madeira, Canaries)
Marine Biology (1996)
-
Genetic polymorphisms in subterranean mammals (Spalax ehrenbergi superspecies) in the Near East revisited: patterns and theory
Heredity (1994)
-
Australopithecines: Ancestors of the African Apes?
Human Evolution (1994)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.