Abstract
A seven-membered microbial community capable of utilising the herbicide Dalapon has been isolated by continuous-flow enrichment culture. The composition of this community has remained remarkably stable over thousands of hours in a Dalapon-limited chemostat. During this period, however, one member of the community, Pseudomonas putida, acquired the ability to grow on Dalapon through the evolution of an extant dehalogenase.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Veldkamp, H., and Jannasch, H. W., J. appl. Chem. Biotechnol., 22, 105–123 (1972).
Veldkamp, H., Sixth International Symposium on Continuous Culture (edit. by Dean, A. C. R., Ellwood, D. C., Evans, C. G. T., and Melling, J.) (in the press, 1976).
Kearney, P. C., Kaufman, D. D., and Beall, M. L., Biochem. biophys. Res. Commun., 14, 29–33 (1964).
Shewan, J., Hobbs, G., and Hodgkiss, W., J. appl. Bact., 23, 379–390 (1960).
Powell, E. O., J. gen. Microbiol., 18, 259–268 (1958).
Slater, J. H., Bull, A. T., and Senior, E., Proc. Soc. gen. Microbiol., 3, 113 (1976).
Clarke, P. H., in Evolution in the Microbial World (edit. by Carlile, M. J., and Skehel, J. J.), (Cambridge University Press, London, 1974).
Hartley, B. S., in Evolution in the Microbial World (edit. by Carlile, M. J., and Skehel, J. J.), (Cambridge University Press, London, 1974).
Vogel, A. I., A Textbook of Quantitative Inorganic Analysis, third ed. (Longman, London, 1962).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Senior, E., Bull, A. & Slater, J. Enzyme evolution in a microbial community growing on the herbicide Dalapon. Nature 263, 476–479 (1976). https://doi.org/10.1038/263476a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/263476a0
This article is cited by
-
l-2-Haloacid dehalogenase (DehL) from Rhizobium sp. RC1
SpringerPlus (2016)
-
The renaissance of continuous culture in the post-genomics age
Journal of Industrial Microbiology & Biotechnology (2010)
-
Biosynthesis of the proteasome inhibitor syringolin A: the ureido group joining two amino acids originates from bicarbonate
BMC Biochemistry (2009)
-
Interactions between populations ofPseudomonas putida leading to the expression of a cryptic dehalogenase gene (dehll)
World Journal of Microbiology & Biotechnology (1995)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.