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Structure of locust adipokinetic hormone, a neurohormone that regulates lipid utilisation during flight

Nature volume 263, pages 207–211 (1976)Cite this article

Abstract

Adipokinetic hormone, isolated from locust corpora cardiaca, has been identified as a blocked pep-tide : PCA–Leu–Asn–Phe–Thr–Pro–Asn–Trp–Gly–Thr–NH2. The detailed structure is based on mass spectrometric data, substantiated in part by dansylEdman and carboxypeptidase data on thermolytic fragments. This is the first peptide hormone from an insect neuroendocrine organ to be fully characterised.

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Author information

Authors and Affiliations

  1. Department of Zoology,

    Judith V. Stone & William Mordue

  2. Department of Biochemistry, Imperial College, London, SW7 2AZ, UK

    Karen E. Batley & Howard R. Morris

Authors
  1. Judith V. Stone
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  2. William Mordue
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  3. Karen E. Batley
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  4. Howard R. Morris
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Stone, J., Mordue, W., Batley, K. et al. Structure of locust adipokinetic hormone, a neurohormone that regulates lipid utilisation during flight. Nature 263, 207–211 (1976). https://doi.org/10.1038/263207a0

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  • DOI: https://doi.org/10.1038/263207a0

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