Abstract
HAEMOFLAGELLATES are protozoan parasites responsible for many important diseases of man and domestic animals1. Leishmania donovani, the cause of visceral leishmaniasis or kala azar, is a widespread human parasitic haemoflagellate. Its life cycle involves man (and other mammals) and an insect vector (sandflies) with a different stage in each of the two host types. Transformation from one stage to the next includes morphological antigenic, physiological, and infectivity changes2–5.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Hoare, C. A., Trypanosomes of Mammals, 60–80 (Blackwell Scientific, Oxford, 1972).
Simpson, L., J. Protozool., 15, 210–207 (1968).
Honiberg, B. M., in Chemical Zoology, 1 (edit. by Florkin. M. and Scheen B. T.) 711–759 (Academic, New York and London, 1967).
Bowman, I. B. R., Srivistava, H. K., and Flynn, I. W., in Comparative Biochemistry of Parasites (edit by Van Den Bossche, H.), 329–342 (Academic New York and London, 1972).
von Brand, T., Biochemistry of Parasites, 368–425 (Academic, New York and London, 1973).
Stevens, L. A., J. Parasitol., 56 (II), 330 (1970).
Berens, R., Brun, R., and Krassner, S. M., J. Parasitol. (in the press).
Rutter, W. M., Pictet, R. L., and Morris, P. W., A. Rev. Biochem., 42, 601–646 (1973).
Pastan, I. H., Johnson, G. S., and Anderson, W. B., A. Rev. Biochem., 44, 491–522 (1975).
Kolb, W. P., Williams, T. W., and Granger, G. A., in In Vitro Methods in Cell-Mediated Immunity (edit. by Bloom, B. and Glade, P.), 333–342 (Academic, New York and London, 1971).
Lamy, L. H., Protistologica, 6, 457–466 (1970).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BRUN, R., BERENS, R. & KRASSNER, S. Inhibition of Leishmania donovani transformation by hamster spleen homogenates and active human lymphocytes. Nature 262, 689–691 (1976). https://doi.org/10.1038/262689a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/262689a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
