Cellular basis for the T wave of the electrocardiogram

Abstract

Differences in action potential duration in different regions of the mammalian ventricle are not systematically present when quiescent tissue is first stimulated, but develop rapidly during repetitive activity. The effects of ouabain and temperature suggest the involvement of the Na+–K+ exchange pump.

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References

  1. 1

    Burgess, M. J., Green, L. S., Millar, K., Wyatt, R., and Abildskov, J. A., Am. Heart J., 84, 660–669 (1972).

  2. 2

    Spach, M. S., and Barr, R. C., Circulation Res., 37, 243–257 (1975).

  3. 3

    Mines, G. R., J. Physiol., Lond., 46, 188–235 (1913).

  4. 4

    Solbery, L. E., Singer, D. H., Ten Eick, R. E., and Duffin, E. G., Circulation Res., 30, 783–797 (1974).

  5. 5

    Noble, D., and Tsien, R. W., in Electrical Phenomena in the Heart (edit. by de Mello, W. F.), 133–161 (Academic, New York, 1972).

  6. 6

    Hauswirth, O., Noble, D., and Tsien, R. W., J. Physiol., Lond., 222, 27–51 (1972).

  7. 7

    Cohen, I., Daut, J., and Noble, D., J. Physiol., Lond. (in the press).

  8. 8

    Mobley, B. A., and Page, E., J. Physiol., Lond., 220, 547–563 (1972).

  9. 9

    Page, S., and Niedergerke, R., J. cell. Sci., 11, 179–203 (1972).

  10. 10

    Hellam, D. C., and Studt, J. W., J. Physiol., Lond., 243, 637–660 (1974).

  11. 11

    Noble, S. J., J. Physiol., Lond. (in the press).

  12. 12

    Cohen, I., Daut, J., and Noble, D., J. Physiol., Lond. (in the press).

  13. 13

    Weidmann, S., J. Physiol., Lond., 132, 157–163 (1956).

  14. 14

    Noble, D., J. cell. comp. Physiol., 66, Suppl. 2, 127–136 (1965).

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