Cellular basis for the T wave of the electrocardiogram


Differences in action potential duration in different regions of the mammalian ventricle are not systematically present when quiescent tissue is first stimulated, but develop rapidly during repetitive activity. The effects of ouabain and temperature suggest the involvement of the Na+–K+ exchange pump.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1

    Burgess, M. J., Green, L. S., Millar, K., Wyatt, R., and Abildskov, J. A., Am. Heart J., 84, 660–669 (1972).

  2. 2

    Spach, M. S., and Barr, R. C., Circulation Res., 37, 243–257 (1975).

  3. 3

    Mines, G. R., J. Physiol., Lond., 46, 188–235 (1913).

  4. 4

    Solbery, L. E., Singer, D. H., Ten Eick, R. E., and Duffin, E. G., Circulation Res., 30, 783–797 (1974).

  5. 5

    Noble, D., and Tsien, R. W., in Electrical Phenomena in the Heart (edit. by de Mello, W. F.), 133–161 (Academic, New York, 1972).

  6. 6

    Hauswirth, O., Noble, D., and Tsien, R. W., J. Physiol., Lond., 222, 27–51 (1972).

  7. 7

    Cohen, I., Daut, J., and Noble, D., J. Physiol., Lond. (in the press).

  8. 8

    Mobley, B. A., and Page, E., J. Physiol., Lond., 220, 547–563 (1972).

  9. 9

    Page, S., and Niedergerke, R., J. cell. Sci., 11, 179–203 (1972).

  10. 10

    Hellam, D. C., and Studt, J. W., J. Physiol., Lond., 243, 637–660 (1974).

  11. 11

    Noble, S. J., J. Physiol., Lond. (in the press).

  12. 12

    Cohen, I., Daut, J., and Noble, D., J. Physiol., Lond. (in the press).

  13. 13

    Weidmann, S., J. Physiol., Lond., 132, 157–163 (1956).

  14. 14

    Noble, D., J. cell. comp. Physiol., 66, Suppl. 2, 127–136 (1965).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Further reading


By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.