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Binding of human immunoglobulins to pituitary ACTH cells

Nature volume 261, pages 142–144 (1976)Cite this article

Abstract

WE report the unexpected finding that the adrenocortico-tropic hormone (ACTH)-secreting cells of the human anterior pituitary gland show an affinity for human immunoglobulins resembling that of normal mast cells for IgE. This phenomenon could have physiological significance if considered in relation to the messages leading to synthesis or release of the hormone.

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Authors and Affiliations

  1. Department of Immunology, The Middlesex Hospital Medical School, London, W1P 9PG, UK

    ANNICK POUPLARD, GIAN-FRANCO BOTTAZZO, DEBORAH DONIACH & IVAN M. ROITT

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  1. ANNICK POUPLARD
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  2. GIAN-FRANCO BOTTAZZO
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  3. DEBORAH DONIACH
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  4. IVAN M. ROITT
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POUPLARD, A., BOTTAZZO, GF., DONIACH, D. et al. Binding of human immunoglobulins to pituitary ACTH cells. Nature 261, 142–144 (1976). https://doi.org/10.1038/261142a0

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  • DOI: https://doi.org/10.1038/261142a0

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