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Spermatogenic failure of translocation heterozygotes affected by H–2-linked gene in mouse

Nature volume 260, pages 143–145 (1976)Cite this article

Abstract

ACCORDING to Lifschytz and Lindsley1,2, the basic control mechanism of spermatogenesis of all male heterogametic organisms consists of inactivation of the X chromosome during differentiation of germ cells. The absence of this control mechanism in female meiosis, where both X chromosomes are active3,4, could explain why only male gametogenesis is impaired in the carriers of some chromosomal aberrations.

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  1. Institute of Molecular Genetics, Czechoslovak Academy of Sciences, 142 20, Prague, 4, Czechoslovakia

    J. FOREJT

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FOREJT, J. Spermatogenic failure of translocation heterozygotes affected by H–2-linked gene in mouse. Nature 260, 143–145 (1976). https://doi.org/10.1038/260143a0

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