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Stable nuclear activation dependent on a protein synthesised during oogenesis

Abstract

A protein synthesised during oogenesis seems to be essential for the activation, during blastulation, of the nuclear genes essential for gastrulation and organogenesis. Nuclear transplantation experiments show that this interaction between the protein and the blastula nucleus produces a heritable state of nuclear activation.

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Brothers, A. Stable nuclear activation dependent on a protein synthesised during oogenesis. Nature 260, 112–115 (1976). https://doi.org/10.1038/260112a0

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