Abstract
MICROTUBULES are fibres, sometimes many micrometres long, present in all eukaryotic cells, formed by the reversible polymerisation of the protein tubulin. These fibres not only have a structural role, but the process of their assembly and disassembly itself controls several cell functions1.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Olmsted, J. B., and Borisy, G. G., A. Rev. Biochem., 42, 507–540 (1973).
Kirschner, M. W., Williams, R. C., Weingarten, M., and Gerhart, J. C., Proc. natn. Acad. Sci. U.S.A., 71, 1159–1163 (1974).
Weingarten, M. D., Lockwood, A. H., Hwo, S.-Y., and Kirschner, M. W., Proc. natn Acad. Sci. U.S.A., 72, 1858–1862 (1975).
Gaskin, F., Cantor, C. R., and Shelanski, M. L., J. molec. Biol., 89, 737–758 (1974).
Salmon, E. D., J. Cell Biol., 66, 114–127 (1975).
Salmon, E. D., Science, 189, 884–886 (1975).
Olmsted, J. B., Marcum, J. M., Johnson, K. A., Allen, C., and Borisy, G. G., J. supramolec. Struct., 2, 429–450 (1974).
Collen, Vandereycken, G., and De Maeyer, L., Nature, 228, 669–671 (1970).
Gerber, B. R., and Noguchi, H., J. molec. Biol., 26, 197–210 (1967).
Heremans, K. A. H., Proc. Int. Conf. High Pressure, Kyoto, 627–630 (The Physico-Chemical Society of Japan, 1974).
O'Connor, T. M., Houston, L. L., and Samson, F., Proc. natn Acad. Sci. U.S.A., 71, 4198–4202 (1974).
Marsland, D., in High Pressure Effects on Cellular Processes (edit. by Zimmerman A. M.), 259 (Academic, New York, 1970).
Oosawa, F., J. theor. Biol., 27, 69–86 (1970).
Dentler, W. L., Granett, S., Witman, G. B., and Rosenbaum, J. L., Proc. natn Acad. Sci. U.S.A., 71, 1710–1714 (1974).
Heremans, K. A. H., Snauwaert, J., Vandersypen, H. A., and Van Nuland, Y., Proc. Int. Conf. High Pressure, Kyoto, 623–626 (The Physico-Chemical Society of Japan, 1974).
Shelanski, M. L., Gaskin, F., and Cantor, C. R., Proc. natn Acad. Sci. U.S.A., 70, 765–768 (1973).
Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., J. biol. Chem., 193, 265–275 (1951).
Ventilla, M., Cantor, C. R., and Shelanski, M., Biochemistry, 11, 1554–1561 (1972).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ENGELBORGHS, Y., HEREMANS, K., DE MAEYER, L. et al. Effect of temperature and pressure on polymerisation equilibrium of neuronal microtubules. Nature 259, 686–689 (1976). https://doi.org/10.1038/259686a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/259686a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
