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Migration and chemotaxis of anucleate cytoplasmic leukocyte fragments

Nature volume 258, pages 723–724 (1975)Cite this article

Abstract

KNOWLEDGE of the mechanisms involved in leukocyte locomotion is limited. Although it is known that amoebae require a nucleus for locomotion1,2 no similar studies have been done with leukocytes. Nothing precise is known about the cellular factors involved in the perception of a chemotactic gradient and the translation of this information into directional migration. We have investigated this problem using anucleate cytoplasmic fragments and heat-polarised granulocytes.

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References

  1. Comandon, J., and Defonbrune, P., C.r. Soc. Biol., 130, 740–748 (1939).

    Google Scholar 

  2. Goldstein, L., and Jelinek, W., Expl Cell Res., 43, 51–55 (1966).

    Article  CAS  Google Scholar 

  3. Keller, H. U., and Bessis, M., Nouv. Rev. Franc. Hem. (in the press).

  4. Bessis, M., and Burtè, B., Texas Rep. biol., Med. Suppl. 1, 23, 204–212 (1965).

    Google Scholar 

  5. Griffin, F. M., and Silverstein, S. C., J. exp. Med., 139, 323–336 (1974).

    Article  CAS  Google Scholar 

  6. Bettex-Galland, M., and Lüscher, E. F., Adv. Protein. Chem., 20, 1–35 (1965).

    Article  CAS  Google Scholar 

  7. Keller, H. U., and Sorkin, E., Int. Archs Allergy appl. Immun., 31, 576–586 (1967).

    Google Scholar 

  8. Zigmond, S., Nature, 249, 450–452 (1974).

    Article  ADS  CAS  Google Scholar 

  9. Becker, E. L., The Phagocytic Cell in Host Resistance, 1–14 (Raven, New York, 1975.)

    Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Pathology, University of Bern, Switzerland

    H. U. KELLER

  2. Institut de Pathologie Cellulaire (INSERM, unité 48), Hôpital de Bicêtre, 94270, Kremlin-Bicêtre, France

    M. BESSIS

Authors
  1. H. U. KELLER
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  2. M. BESSIS
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KELLER, H., BESSIS, M. Migration and chemotaxis of anucleate cytoplasmic leukocyte fragments. Nature 258, 723–724 (1975). https://doi.org/10.1038/258723a0

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  • DOI: https://doi.org/10.1038/258723a0

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