Article | Published:

Three-dimensional model of purple membrane obtained by electron microscopy

Naturevolume 257pages2832 (1975) | Download Citation

Subjects

Abstract

A 7-Å resolution map of the purple membrane has been obtained by electron microscopy of tilted, unstained specimens. The protein in the membrane contains seven, closely packed, α-helical segments which extend roughly perpendicular to the plane of the membrane for most of its width. Lipid bilayer regions fill the spaces between the protein molecules.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1

    Stoeckenius, W., and Kunau, W. H., J. Cell Biol., 38, 337–357 (1968).

  2. 2

    Oesterhelt, D., and Stoeckenius, W., Proc. natn. Acad. Sci. U.S.A., 70, 2853–2857 (1973).

  3. 3

    Oesterhelt, D., and Stoeckenius, W., Nature new Biol., 233, 149–152 (1971).

  4. 4

    Blaurock, A. E., and Stoeckenius, W., Nature new Biol., 233, 152–155 (1971).

  5. 5

    Unwin, P. N. T., and Henderson, R., J. molec. Biol., 94, 425–440 (1975).

  6. 6

    De Rosier, D. J., and Klug, A., Nature, 217, 130–134 (1968).

  7. 7

    Henderson, R., J. molec. Biol., 93, 123–138 (1975).

  8. 8

    Glaeser, R. M., in Physical Aspects of Electron Microscopy and Microbeam Analysis (edit. by Siegel, B., and Beaman, D. R.), 205 (Wiley, New York, 1975).

  9. 9

    Blaurock, A. E., J. molec. Biol., 93, 139–158 (1975).

  10. 10

    Crick, F. H. C., Acta Cryst., 6, 689–697 (1953).

  11. 11

    Singer, S. J., and Nicholson, G. L., Science, 175, 720–731 (1972).

  12. 12

    Bretscher, M. S., Science, 181, 622–629 (1973).

Download references

Author information

Affiliations

  1. MRC Laboratory of Molecular biology, Hills Road, Cambridge, CB2 2QH, UK

    • R. Henderson
    •  & P. N. T. Unwin

Authors

  1. Search for R. Henderson in:

  2. Search for P. N. T. Unwin in:

About this article

Publication history

Received

Accepted

Issue Date

DOI

https://doi.org/10.1038/257028a0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.