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Nucleotide sequence of a viral RNA fragment that binds to eukaryotic ribosomes

Nature volume 256, pages 624–628 (1975)Cite this article

Abstract

The nucleotide sequence has been determined for the first 53 bases of brome mosaic virus RNA4, the monocistronic messenger for brome mosaic virus coat protein. The sequence includes the binding site for wheat embryo ribosomes. The 5′-terminal base is a modified guanosine attached to the penultimate base through a 5′ p-p-p 5′ link. The initiating AUG codon is only 10 nucleotides from the 5′-terminus. The 13 triplets following the AUG codon correspond to the known sequence of brome mosaic virus coat protein.

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Authors and Affiliations

  1. Biophysics Laboratory of the Graduate School, and Biochemistry Department of the College of Agricultural and Life Sciences, University of Wisconsin, Madison, Wisconsin, 53706

    Ranjit Dasgupta, Ding S. Shih, Chris Saris & Paul Kaesberg

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  1. Ranjit Dasgupta
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  2. Ding S. Shih
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  3. Chris Saris
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  4. Paul Kaesberg
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Dasgupta, R., Shih, D., Saris, C. et al. Nucleotide sequence of a viral RNA fragment that binds to eukaryotic ribosomes. Nature 256, 624–628 (1975). https://doi.org/10.1038/256624a0

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