Letter | Published:

Effects of structural defects in sonicated phospholipid vesicles on fusion and ion permeability

Naturevolume 256pages584586 (1975) | Download Citation



ULTRASONICATED lecithin–water dispersions, consisting of single-walled bilayer vesicles, are used as a model for the phospholipid bilayer in biomembranes and have the unique advantage of a well-defined inside and outside1,2. The system is well suited, therefore, for studies of transport of solutes across the bilayer membrane3. Fusion of these structures may also be used as a model for cell fusion, endocytosis and related phenomena4,5.

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    Present address: Département de Recherche Fondamentale, Centre d'Etudes Nucléaires de Grenoble, France


  1. A. A. Noyes Laboratory of Chemical Physics, California Institute of Technology, Pasadena, California, 91125

    •  & SUNNEY I. CHAN


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