Letter | Published:

Effects of structural defects in sonicated phospholipid vesicles on fusion and ion permeability

Naturevolume 256pages584586 (1975) | Download Citation

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Abstract

ULTRASONICATED lecithin–water dispersions, consisting of single-walled bilayer vesicles, are used as a model for the phospholipid bilayer in biomembranes and have the unique advantage of a well-defined inside and outside1,2. The system is well suited, therefore, for studies of transport of solutes across the bilayer membrane3. Fusion of these structures may also be used as a model for cell fusion, endocytosis and related phenomena4,5.

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Author notes

    • JEAN-LUC GIRARDET

    Present address: Département de Recherche Fondamentale, Centre d'Etudes Nucléaires de Grenoble, France

Affiliations

  1. A. A. Noyes Laboratory of Chemical Physics, California Institute of Technology, Pasadena, California, 91125

    • RÜDIGER LAWACZECK
    • , MASATSUNE KAINOSHO
    • , JEAN-LUC GIRARDET
    •  & SUNNEY I. CHAN

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https://doi.org/10.1038/256584a0

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