Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Possible mechanism for action of prolactin on mammary cell sodium transport

Abstract

PROLACTIN, like other polypeptide and glycoprotein hormones from the pituitary gland, exerts its effects on target cells through interaction with receptors on the plasma membrane1–4. Unlike several other pituitary hormones, this does not occur through activation of adenyl cyclase5, and the mechanism of action of prolactin must therefore lie elsewhere.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Turkington, R. W., Biochem. biophys. Res. Commun., 41, 1362–1367 (1970).

    Article  CAS  Google Scholar 

  2. Birkinshaw, M., and Falconer, I. R., J. Endocr., 55, 323–334 (1972).

    Article  CAS  Google Scholar 

  3. Shiu, R. P. C., and Friesen, H. G., J. biol. Chem., 249, 7902–7911 (1974).

    CAS  PubMed  Google Scholar 

  4. Shiu, R. P. C., and Friesen, H. G., Biochem. J., 140, 301–311 (1974).

    Article  CAS  Google Scholar 

  5. Turkington, R. W., in Lactogenic Hormones (edit. by Wolstenholme, G. E. W., and Knight, J.), 111–127 (Churchill–Livingstone, Edinburgh and London, 1972).

    Google Scholar 

  6. Ensor, D. M., and Ball, J. N., Fedn Proc., 31, 1615–1623 (1972).

    CAS  Google Scholar 

  7. Hart, I. C., J. Endocr., 57, 179 (1973).

    Article  CAS  Google Scholar 

  8. Skou, J. C., Physiol. Rev., 45, 596–617 (1965).

    Article  CAS  Google Scholar 

  9. Cotlove, E., Tranthan, H. V., and Bowman, R. L., J. Lab. clin. Med., 31, 461–468 (1958).

    Google Scholar 

  10. Kinura, T. J., Japan Obstet. Gynec. Soc., 21, 301–308 (1969).

    Google Scholar 

  11. Cowie, A. T., J. Endocr., 44, 437–450 (1969).

    Article  CAS  Google Scholar 

  12. Linzell, J. M., and Peaker, J. L., Physiol. Rev., 51, 564–597 (1971).

    Article  CAS  Google Scholar 

  13. Kroeger, H., in Endocrine Genetics (edit. by Spickett, S. G.), Endocr. Soc. Symp., 15, 55–66 (Cambridge University Press, Cambridge, 1967).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

FALCONER, I., ROWE, J. Possible mechanism for action of prolactin on mammary cell sodium transport. Nature 256, 327–328 (1975). https://doi.org/10.1038/256327a0

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/256327a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing