Abstract
THE fundamental importance of specific cellular interaction is indicated by its ubiquity in biological systems. Such specificity must be mediated by macromolecular recognition of intrinsically the same nature as enzyme–substrate binding and antigen–antibody interactions, but few systems involving recognition between two cells or two organisms are readily amenable to investigation at the molecular level. The attachment of bacteriophage to its host is an exception, and the chemical constitution of the specific receptor site involved in the initial binding of phage T4 to Escherichia coli B has therefore been examined.
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DAWES, J. Characterisation of the bacteriophage T4 receptor site. Nature 256, 127–128 (1975). https://doi.org/10.1038/256127a0
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DOI: https://doi.org/10.1038/256127a0
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