Abstract
THE intensity of body and tissue protein metabolism per kg declines with increased adult body size in mammals1. This fall parallels a similar progressive decline in the intensity of energy metabolism2–4. It has also been concluded that protein metabolism per unit of body weight is about four to five times faster in young rats than in adult man1; this pattern of change extends to cellular and subcellular aspects of protein metabolism, such as plasma albumin synthesis, liver RNA content and enzyme activity1,5. Similarly, the rate of protein synthesis per kg total body weight declines during growth and development within a species, such as the rat6. This parameter again parallels the reduction in the intensity of energy metabolism which occurs during the growth period3.
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YOUNG, V., STEFFEE, W., PENCHARZ, P. et al. Total human body protein synthesis in relation to protein requirements at various ages. Nature 253, 192–194 (1975). https://doi.org/10.1038/253192a0
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DOI: https://doi.org/10.1038/253192a0
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