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Sequence analysis of immunoglobulin light chain messenger RNA

Abstract

RNA and DNA sequencing methods are used to define some features, principally at the 3′ terminus, of the structure of immunoglobulin light chain mRNA. The results show that there is one molecule coding for the V and C regions of the light chain and rule out the possibility of two separate molecules.

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Milstein, C., Brownlee, G., Cartwright, E. et al. Sequence analysis of immunoglobulin light chain messenger RNA. Nature 252, 354–359 (1974). https://doi.org/10.1038/252354a0

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