Abstract
THE laminar organisation of neurones in the brain of the homozygous ‘reeler’ mutant mouse1 is grossly disrupted, especially in the cerebellum, hippocampus and neocortex2–6. Although a number of histological studies on synaptic organisation in the cerebellum of various mutants have been reported7–9, the effect of such disorganisation on interneuronal connections has not been investigated electrophysiologically, either in the cerebellum or elsewhere.
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References
Falconer, D. S., J. Genet., 50, 192–201 (1951).
Caviness, V. S., and Sidman, R. L., J. comp. Neurol., 145, 85–104 (1972).
Caviness, V. S., and Sidman, R. L., J. comp. Neurol., 147, 235–254 (1973).
Hamburgh, M., Experientia, 16, 460–461 (1960).
Hamburgh, M., Devl Biol., 8, 165–185 (1963).
Meier, H., and Hoag, W. G., J. Neuropath. exp. Neurol., 21, 649–654 (1962).
Rakic, P., and Sidman, R. L., J. Neuropath. exp. Neurol., 31, 192 (1972).
Rakic, P., and Sidman, R. L., J. comp. Neurol., 152, 133–162 (1973).
Sotelo, C., and Changeux, J.-P., Brain Res., 67, 519–526 (1974).
Lorente de Nó, R., J. Psychol. Neurol., Lpz., 46, 113–177 (1934).
Andersen, P., Bliss, T. V. P., and Skrede, K. K., Expl Brain Res., 13, 222–238 (1971).
Lømo, T., Expl Brain Res., 12, 18–45 (1971).
Angevine, jun., J. B., Expl Neurol., Suppl. 2, 1–70 (1965).
Bliss, T. V. P., Chung, S. H., and Stirling, R. V., J. Physiol., Lond., 239, 92–94P (1974).
Caviness, V. S., J. comp. Neurol., 151, 113–120 (1973).
DeLong, G. R., Devl Biol., 22, 563–583 (1970).
DeLong, G. R., and Sidman, R. L., Devl. Biol., 22, 584–600 (1970).
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BLISS, T., CHUNG, S. An electrophysiological study of the hippocampus of the ‘reeler’ mutant mouse. Nature 252, 153–155 (1974). https://doi.org/10.1038/252153a0
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DOI: https://doi.org/10.1038/252153a0
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