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Gene deletion as the cause of α thalassaemia: The severe form of α thalassaemia is caused by a haemoglobin gene deletion

Nature volume 251, pages 389–392 (1974)Cite this article

Abstract

Two independent groups show that the absence of all or part of the globin α-chain gene is the origin of the homozygous α thalassaemia.

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Author information

Authors and Affiliations

  1. Beatson Institute for Cancer Research, Glasgow, G3 6UD, UK

    SERGIO OTTOLENGHI, W. GEORGE LANYON, JOHN PAUL & ROBERT WILLIAMSON

  2. Department of Haematology, University of Liverpool, UK

    D. J. WEATHERALL, J. B. CLEGG & JON PRITCHARD

  3. Division of Haematology, Mahidol University, of Bangkok, Thailand

    S. POOTRAKUL

  4. Department of Paediatrics, University of Singapore,

    WONG HOCK BOON

Authors
  1. SERGIO OTTOLENGHI
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  2. W. GEORGE LANYON
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  3. JOHN PAUL
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  4. ROBERT WILLIAMSON
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  5. D. J. WEATHERALL
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  6. J. B. CLEGG
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  7. JON PRITCHARD
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  8. S. POOTRAKUL
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  9. WONG HOCK BOON
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OTTOLENGHI, S., LANYON, W., PAUL, J. et al. Gene deletion as the cause of α thalassaemia: The severe form of α thalassaemia is caused by a haemoglobin gene deletion. Nature 251, 389–392 (1974). https://doi.org/10.1038/251389a0

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  • DOI: https://doi.org/10.1038/251389a0

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