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Surface antigen(s) common to human astrocytoma cells

Nature volume 250, pages 328–330 (1974)Cite this article

Abstract

SINCE animal tumours induced by viruses exhibit common antigenic properties1, the extent to which antigens are shared in human tumours is of obvious interest. Such antigenic cross reactions between human tumours of the same histological origin have been demonstrated by cell-mediated colony inhibition testing as well as by serological means2,3. But few immunological studies of human brain tumours have been reported. Studying the cytotoxic effect of patients' lymphocytes on autologous or allogeneic astrocytomas, some workers have found antigenic cross reaction4 while others have not5. I report here the serological demonstration of surface antigen(s) common to cultured human astrocytoma cells.

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References

  1. Klein, G., A. Rev. Microbiol., 20, 223 (1966).

    Article  CAS  Google Scholar 

  2. Hellström, I., Hellström, K. E., Sjogren, H. O., and Warner, G. A., Int. J. Cancer, 7, 1 (1971).

    Article  Google Scholar 

  3. Morton, D. L., Malmgren, R. A., Hall, W. T., and Shidlovsky, G., Surgery, 66, 152 (1969).

    CAS  PubMed  Google Scholar 

  4. Kumar, S., Taylor, G., Steward, J. K., Waghe, M. A., and Morris-Jones, P., Int. J. Cancer, 12, 194 (1973).

    Article  CAS  Google Scholar 

  5. Levy, N. L., Mahaley, M. S., and Day, E. D., Cancer Res., 32, 477 (1972).

    CAS  PubMed  Google Scholar 

  6. Boyse, E. A., Old, L. J., and Chuuroulinkov, I., Methods in Medical Research, IV, 39, (Year Book Medical Publishers, Chicago, 1964).

    Google Scholar 

  7. Boyse, E. A., and Old, L. J., A. Rev. Genet., 3, 269 (1969).

    Article  Google Scholar 

  8. Bhattacharya, M., and Barlow, J. J., Cancer, 31, 588 (1973).

    Article  CAS  Google Scholar 

  9. Bloom, H. J. G., Peckham, M. J., Richardson, A. E., Alexander, P. A., and Payne, P. M., Br. J. Cancer, 27, 253 (1973).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Biochemical Pathology, University College Hospital Medical School, University Street, London, WC1E 6JJ, UK

    HUGH COAKHAM

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  1. HUGH COAKHAM
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COAKHAM, H. Surface antigen(s) common to human astrocytoma cells. Nature 250, 328–330 (1974). https://doi.org/10.1038/250328a0

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