Abstract
Computer-aided reconstruction of immature brain cells with highly irregular shapes from serial electron microscopic montages gives three-dimensional images and quantitative data on surface areas and volumes, providing new classes of data on cell behaviour during development.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Golgi, C., Sulla fina anatomia degli organi centrali del sistema nervoso, 1883, republished in Opera Omnia (Hoepli, Milan, 1903).
Scheibel, M. E., and Scheibel, A. B., Int. Rev. Neurobiol., 13, 1 (1970).
Wann, D. F., Woolsey, T. A., Dierker, M. L., and Cowan, W. M., Inst. Elect. Electron. Engng, Trans. Biomed. Engng, 20, 233 (1973).
Levinthal, C., and Ware, R., Nature, 236, 207 (1972).
Macagno, E. R., Lopresti, V., and Levinthal, C., Proc. natn. Acad. Sci. U.S.A., 70, 57 (1973).
Rakic, P., J. comp. Neurol., 145, 61 (1972).
Boulder Committee, Anat. Rec., 166, 257 (1970).
Willey, T. J., Schultz, R. L., and Gott, A. H., Inst. Elect. Electron. Engng, Trans. Biomed. Engng, 20, 288 (1973).
Stensaas, L. J., and Stensaas, S. S., Z. Zellforsch., 91, 341 (1968).
Rakic, P., Brain Res., 33, 471 (1971).
Bray, D., and Bunge, M. B., Locomotion of Tissue Cells, Ciba Foundation Symp., 14, 195 (1973).
Sjöstrand, F. S., J. ultrastruct. Res., 2, 122 (1958).
Karlsson, U., J. ultrastruct. Res., 16, 482 (1966).
Rakic, P., Science, 183, 425 (1974).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Rakic, P., Stensas, L., Sayre, E. et al. Computer-aided three-dimensional reconstruction and quantitative analysis of cells from serial electron microscopic montages of foetal monkey brain. Nature 250, 31–34 (1974). https://doi.org/10.1038/250031a0
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1038/250031a0
This article is cited by
-
Development of prefrontal cortex
Neuropsychopharmacology (2022)
-
P-Rex1 Overexpression Results in Aberrant Neuronal Polarity and Psychosis-Related Behaviors
Neuroscience Bulletin (2019)
-
Variations in brain defects result from cellular mosaicism in the activation of heat shock signalling
Nature Communications (2017)
-
Decoding the molecular mechanisms of neuronal migration using in utero electroporation
Medical Molecular Morphology (2016)
-
Ezh2 is involved in radial neuronal migration through regulating Reelin expression in cerebral cortex
Scientific Reports (2015)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.